The multidisciplinary study of complex systems in the physical and social sciences over the past quarter of a century has led to the articulation of important new conceptual perspectives and methodologies that are of value both to researchers in these fields as well as to professionals, policymakers, and citizens who must deal with challenging social and global problems in the 21st century. The main goals of this article are to (a) argue for the importance of learning these ideas at the precollege and college levels; (b) discuss the significant challenges inherent in learning complex systems knowledge from the standpoint of learning sciences theory and research; (c) discuss the “learnability issue” of complex systems conceptual perspectives and review a body of literature that has been exploring how learning sciences pedagogical approaches can lead to student learning of important dimensions of complex systems knowledge; (d) argue that the cognitive and sociocultural factors related to learning complex systems knowledge are relevant and challenging areas for learning sciences research; and (e) consider ways that concepts and methodologies from the study of complex systems raise important issues of theoretical and methodological centrality in the field of the learning sciences itself. (view/download full-text pdf)